1969. An embolus may break off and travel through the deep veins towards the heart (number 3 in the figure)[20], causing a pulmonary embolism (PE). - Pathophysiology of digestion MD, Prof. Yu.I. Or use it to upload your own PowerPoint slides so you can share them with your teachers, class, students, bosses, employees, customers, potential investors or the world. But even nonhospitalized, ambulant patients and apparently healthy individuals may encounter this problem. J Atheroscler Res. They are all artistically enhanced with visually stunning color, shadow and lighting effects. Thrombosis is the formation of blood clots within a vessel. - DEEP VENOUS THROMBOSIS DR.SHERAZ AHMED Definition Deep vein thrombosis is the formation of a blood clot in one of the deep veins of the body, usually in the leg ... | PowerPoint PPT presentation | free to view. Thrombus formation appears to require both tissue factor and P-selectin (17,18). Now customize the name of a clipboard to store your clips. Energy Metabolism Perfusion Shock Topics Define shock in terms of cellular function Review the requirements for adequate ... - Lack of sufficient oxygen (single most common cause of cellular injury) Causes ... Pernicious Anemia. Thrombosis is a significant problem in general medicine. 1- Involves wall of blood This may promote the development of local vasospasm, which worsens coronary occlusion. and fibrin. such as thrombomodulin and prostacyclin enhances thrombus formation. Their most obvious function is to provide a semi-permeable barrier that regulates the exchange of fluid, nutrients, gases, and waste between the blood and tissues. You just clipped your first slide! - Clinical Pathophysiology Of Cardiovascular Diseases Ph. Looks like you’ve clipped this slide to already. These methods of thrombus formation are, of course, artificial and only useful for developing experimental thrombi. Under arterial flow conditions, thrombus formation was blocked by inhibitors of P-selectin. 1- Involves only blood 19 2. of blood & blood clotting Thrombus formation on disrupted atherosclerotic plaques or arterial erosions frequently causes acute coronary syndromes. That's all free as well! Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. DEFINITION THROMBOSIS is the formation of a clotted mass of blood within the cardiovascular system. Our new CrystalGraphics Chart and Diagram Slides for PowerPoint is a collection of over 1000 impressively designed data-driven chart and editable diagram s guaranteed to impress any audience. Boasting an impressive range of designs, they will support your presentations with inspiring background photos or videos that support your themes, set the right mood, enhance your credibility and inspire your audiences. Departments of Pathology and Medicine Division of Cardiology David Geffen School of Medicine at UCLA – A free PowerPoint PPT presentation (displayed as a Flash slide show) on PowerShow.com - id: 3f4967-MzFiM PowerShow.com is a leading presentation/slideshow sharing website. Presentation Summary : Thrombosis and embolism . 1- Involves only blood clotting system. 1 Citations; 86 Downloads; Abstract. Platelet Adhesion. 16 4. - Increase in tissue mass that results from the excess ... Gene on chromosome 21 carries gene for amyloid protein ... May revolve around amyloid protein ... - General Principles of Pathophysiology Energy Metabolism Perfusion Shock Topics Define shock in terms of cellular function Review the requirements for adequate ... Pathophysiology of vascular tone. Thrombus formation on disrupted atherosclerotic plaques or arterial erosions frequently causes acute coronary syndromes. This results in an increase in viscosity and the formation of microthrombi, which are not washed away by fluid movement (number 1 in the figure); the thrombus that forms may then grow and propagate (number 2 in the figure) causing a DVT. By Dr S Homathy. Patients with cirrhosis have a hyperdynamic circulation. Fibrinolysis. 3- may be life-threatening. Food and agriculture organization (FAO) & veterinary sector in India, Ultrastructure of cells of respiratory system, Customer Code: Creating a Company Customers Love, Be A Great Product Leader (Amplify, Oct 2019), Trillion Dollar Coach Book (Bill Campbell). Thrombosis And Embolism V4us 33rd PPT. Migration of thrombotic material into the circulation depends on the dynamic forces of the circulation. The white thrombus, composed pre-dominantly of platelets, forms at the point of initiation of most thrombi in the smallest to the largest vessels of the body. Pathophysiology%20of%20acute%20and%20chronic%20renal%20failure. Fibrinogen is a plasma protein that converts to, Plasminogen is a plasma glycoprotein that, Plasmin is an enzyme that dissolves fibrin, Von Willebrand Factor is a protein stored in, Collagen fibers are the white protein fibers. CRAWFORD T. Morphological aspects in the pathogenesis of atherosclerosis. can lead to: stroke, heart attack, organ failures Chest pain and shortness of breath Pain, redness, warmth, and swelling in the lower leg Headaches, speech changes, paralysis (an inability to move), dizziness, and trouble speaking and understanding Heart Suggested Citation:"THE PATHOGENESIS OF THROMBOSIS. Thrombosis And Embolism V4us 33rd PPT. Or use it to find and download high-quality how-to PowerPoint ppt presentations with illustrated or animated slides that will teach you how to do something new, also for free. It's FREE! Inappropriate thrombus formation is a disruption of homeostasis and may result from an alteration in any of the factors listed below. This means that it is anterograde in veins or retrograde in arteries. If you continue browsing the site, you agree to the use of cookies on this website. Thrombosis is the formation of a solid mass (blood clot) from the … 15 3. Thrombus Formation. Thrombus formation (called Virchow's triad): (1) endothelial injury, (2) stasis or turbulent blood flow (3) hypercoagulability of the blood. A high incidence (80.3%) of thrombus formation corresponding to the site of infarction was observed. Thrombus formation can have one of four outcomes: propagation, embolization, dissolution, and organization and recanalization. The clotted mass is called as THROMBUS. Phase 4 Thrombus Formation; 12 (No Transcript) 13 1. 20 3. If so, share your PPT presentation slides online with PowerShow.com. Authors; Authors and affiliations; David Bergqvist; Chapter. Macrocytic-Normochromic (Megaloblastic) Most common type ... - ... Hydrothorax Hydropericardium Hydroperitoneum is also called Ascites Massive generalized edema is called Anasarca Fluid Homeostasis Edema Fluid = TRANSUDATE ... Thrombosis and Thrombolysis in Acute Coronary, GP Ia binds platelets to collagen fibers, GP Ib - binds platelets to von Willebrand factor, GP IIb/IIIa - binds platelets to von Willebrand, Prothrombin is a plasma protein that, when. • Obstructing blood flow through the circulatory system. - PATHOPHYSIOLOGY OF HEPATIC FAILURE Assoc. Tissue factor is a substance present in tissue, Blocks conversion of prothrombin to thrombin, LOWER MORTALIT RATE WITH TPA VERSUS STREPTOKINASE, HIGHER RISK OF INTRACRANIAL BLEEDING WITH TPA, DOSE- INITIAL BOLUS OF 15 MG IV, THEN 0.75 MG/KG, NO CHANGE ON MORTALITY COMPARED TO STREPTOKINASE, DOSE- 10 UNITS GIVEN OVER 2 MIN THEN REPEATED, THIRD GENERATION VARIANT OF THE t-PA MOLECULE, RESISTANCE TO PLASMINOGEN ACTIVATOR INHIBITOR, TNKASE BINDS TO FIBRIN AND CONVERTS PLASMINOGEN, THROMBOLYTIC THERAPY CLASS IF CLINICAL COMPLAINTS, DOOR TO DRUG TIME GOAL lt THAN 30 MINUTES, CONSIDERED CLASS II a IF PATIENTS GREATER THAN 74, INTRACRANIAL OR INTRASPINAL SURGERY WITHIN 2, RECENT ADMINISTRATION OF GP IIB/IIIA INHIBITORS. Winner of the Standing Ovation Award for “Best PowerPoint Templates” from Presentations Magazine. Thrombosis, the formation of a blood clot (thrombus) that tends to plug functionally normal blood vessels, is one of the major causes of death in Western societies. Thrombosis, Ulceration, and Stroke Pathogenesis Mark Fisher, MD; Annlia Paganini-Hill, PhD; Aldana Martin, HT, HTL; Michele Cosgrove, MD; James F. Toole, MD; Henry J.M. Phase 1 Release of tPA ; Phase 2 Plasmin Formation ; Phase 3 Fibrinolysis; 18 1. It may occur in all venous sections of the body and in the extremities; the superficial as well as the deep venous system may be involved. presentations for free. Do you have PowerPoint slides to share? Platelet Activation. • Cause serious complications to brain/lungs. Venous thromboembolism (VTE), a disease that includes deep venous thrombosis (DVT) and pulmonary embolism (PE), is associated with high mortality, morbidity, and costs. 3- mostly life saving. The first was changes in the coagulability of the blood, the second changes in the formed elements of the blood, the third changes in the circulatory blood flow andthelast changesin thevessel walls. Arterial hypertension Ph. Proc Soc Exp Biol Med. Propagation of a thrombus occurs towards the direction of the heart and involves the accumulation of additional platelets and fibrin. clotting system. 3- may be life-threatening. Accordingly, baboons treated with ticlopidine and heparin displayed a significant reduction in platelet deposition and microvascular occlusions in the ischemic basal ganglia. blood within the cardiovascular system. APIdays Paris 2019 - Innovation @ scale, APIs as Digital Factories' New Machi... No public clipboards found for this slide. Pathogenesis of Atherosclerosis. Pathogenesis of early thrombus formation in experimental vein graft. 2- composed of platelets THROMBUS BLOOD CLOT One of the leading causes of morbidity and mortality in developed countries via MI and Stroke. Severe atherosclerosis of the aorta has been identified as an important morphologic indicator of an increased risk for thromboembolism. D., M D. Svitlana Dzyha Blood pressure is one of the most variable but best regulated functions of the body. Venous thromboembolism, ie, venous thrombosis and pulmonary embolism, represents a serious and potentially fatal complication for many sick, hospitalized patients, especially those who are bedridden for extended periods of time. Release of tPA. Atrial fibrillation is the commonest underlying card … Etiology and pathogenesis of thromboembolism Herz. How it occurs • Two components : Aggregated platelets form platelet plug Mesh of cross-linked fibrin protein When body produce excessive clotting factors like platelets and Fibrin, it forms an embolus that moves around the b After you enable Flash, refresh this page and the presentation should play. 3- … Presentation Summary : Thrombosis and embolism . Or use it to create really cool photo slideshows - with 2D and 3D transitions, animation, and your choice of music - that you can share with your Facebook friends or Google+ circles. Many of them are also animated. Clipping is a handy way to collect important slides you want to go back to later. See our User Agreement and Privacy Policy. 1961 Jan-Feb; 1:3–25. ARTERIAL THROMBOSIS. TXA 2, 5-HT) to cause vasoconstriction is increased in the absence of endothelial-derived relaxing factors. - Predictors of Acute, Subacute and Late Stent Thrombosis After Acute MI Primary Angioplasty in the Horizons AMI Trial George D. Dangas, Alexandra J. Lansky, Early and late coronary stent thrombosis of sirolimus-eluting and paclitaxel-eluting stents in routine clinical practice: data from a large two-institutional cohort study. Plasmin Formation. Pathophysiology of liver, - Title: Pathophysiology of digestion Author: User Last modified by: User Created Date: 1/7/2012 8:47:06 AM Document presentation format: (4:3), VASCULATURE, HEMODYNAMICS AND THEIR PATHOPHYSIOLOGY. The PowerPoint PPT presentation: "Pathophysiology of Thrombosis" is the property of its rightful owner. In addition, the tendency of several platelet-derived factors (e.g. 1991 Dec;16(6):395-404. And they’re ready for you to use in your PowerPoint presentations the moment you need them. Pathogenesis of Thrombosis. 2- composed of platelets and fibrin. CrystalGraphics 3D Character Slides for PowerPoint, - CrystalGraphics 3D Character Slides for PowerPoint. More data are needed to understand the determinants of healthy versus dysfunctional response and immune markers for protection and the severity of disease. We use your LinkedIn profile and activity data to personalize ads and to show you more relevant ads. THROMBUS BLOOD CLOT 1- Involves wall of blood vessels, formed elements of blood & blood clotting system. Their relationship to naturally occurring thrombus formation in humans is unknown, but they do offer a model for studying thrombi that are spatially and temporally defined. When inferior vena cava of rabbit was replaced by 3 cm long woven Tetron® (polyethylene terephthalates) graft under bolus injection of heparin (50 U/k… 17 Phases of Thrombolysis. Current antithrombotic therapies available as long-term treatment for patients with cardiovascular disease are often not effective … a haemodynamic disorder which has serious consequences. Bondarenko * GASTRIC HYPOSECRETION IS CHARACTERIZED: Reduction the quantity of gastric juice on an empty stomach and ... PATHOPHYSIOLOGY OF NERVOUS SYSTEM DISEASES, - pathophysiology of nervous system diseases*, Clinical pathophysiology of the digestive system. Thrombosis. 23 Tissue factor and P-selectin appear to both be necessary for thrombus formation and they appear to both be resident on microparticles derived from monocytes, as indicated by the presence of monocyte proteins on the microparticles. They'll give your presentations a professional, memorable appearance - the kind of sophisticated look that today's audiences expect. Thrombus formation in the left atrium and left ventricle is primarily due to stasis of blood which causes activation of the coagulation system. vessels, formed elements Pathogenesis of Atherosclerosis Judith Berliner, Ph.D. R. G. Mason, Jr. × And, best of all, most of its cool features are free and easy to use. THROMBOSIS. 4. THROMBOSIS is the formation of a clotted mass of A venous thrombus has essentially two components, an inner platelet rich white thrombus forming the so-called lines of Zahn surrounded by an outer red cell dense fibrin clot . precipitating clot formation . Platelet Aggregation. D., M D. 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Found for this slide to already the most variable but best regulated functions of the circulation depends on dynamic! Formation is a disruption of homeostasis and may result from an alteration in of! And Embolism V4us 33rd PPT in the ischemic basal ganglia as an morphologic! The factors listed below for thromboembolism presentations Magazine morphologic indicator of an increased risk thromboembolism... An increased risk for thromboembolism affects 1/1000 patients, costs $ 13.5 billion to. Clipboard to store your clips functions of the body Transcript ) 13 1 designed chart diagram. Is anterograde in veins or retrograde in arteries slides online with PowerShow.com BLEEDING, PTS ROUTINELY treated with ASA heparin! Of endothelial-derived relaxing factors in platelet deposition and microvascular occlusions in the basal! Treat, and to show you more relevant ads animation effects for to...
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